PARTICIPANTS ALREADY ON TAMOXIFEN, BUT OTHER PRIOR TREATMENT ARE ALLOWED PARTICIPANTS WITH AGGRESSIVE DISEASE REQUIRING CYTOTOXIC THERAPY OR LOCOREGIONAL THERAPIES EG HEPATIC EMBOLIZATION A HISTORY OF SERIOUS CLINICAL OR PSYCHIATRIC ILLNESS THAT, BY PARTICIPANTS ALREADY ON TAMOXIFEN, BUT OTHER PRIOR TREATMENT ARE ALLOWED PARTICIPANTS WITH AGGRESSIVE DISEASE REQUIRING CYTOTOXIC THERAPY OR LOCOREGIONAL THERAPIES EG HEPATIC EMBOLIZATION A HISTORY OF SERIOUS CLINICAL OR PSYCHIATRIC ILLNESS THAT, BY
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